The Mediterranean Sea is very sensitive to climatic changes due to its semi-enclosed nature and is therefore defined as one of the hotspots in future climate change projections. In this study, we use Argo float data to assess climatologies and trends in temperature and Ocean Heat Content (OHC) throughout the Mediterranean Sea and for specific sub-basins (e.g. Western and Eastern Mediterranean, Gulf of Lion, South Adriatic). The amount of the OHC, spatially averaged in bins of 1°x1° over the period from 2001 to 2020, increases from west to east in the Mediterranean Sea. Time series of temperature and OHC from 2005 to 2020, estimated in the surface and intermediate layers (5-700 m) and deeper layer (700-2000 m), reveal significant warming tre...