Temporal change and intergroup comparison of vessel area mean blur rate following eye drop administration.

Changes in vessel area mean blur rate as percentages (%MV) during the evaluation of the effects of the eye drops. The left figure shows temporal changes in %MV in the saline group, brinzolamide group, and brinzolamide and brimonidine fixed combination (BBFC) group, respectively, shown by black squares (■), white triangles (△), and black circles (●). The right figure shows intergroup comparisons of %MV 6 hours after administration. Each group had n = 9. Error bars designate SD. *P < 0.05 in a one-way ANOVA followed by the Tukey-Kramer test.