Cardiac troponin T as an adverse prognostic biomarker in established renal failure

Troponin (Tn) proteins are the gold standard of biomarkers in myocardial injury. Both TnT and TnI are sensitive and specific in reflecting myocardial damage; however they do not indicate the mechanism of injury. Troponins can be altered in non-cardiac conditions. Many hypotheses have been put forward for the elevation of troponins in dialysis patients; but how do we interpret the results? This study measured TnT in our haemodialysis population and outcome (mortality) was audited over 36 months