In George Wald's Nobel Prize acceptance speech for "discoveries concerning the primary physiological and chemical visual processes in the eye", he noted that events after the activation of rhodopsin are too slow to explain visual reception. Photoreceptor membrane phosphoglycerides contain near-saturation amounts of the omega-3 fatty acid docosahexaenoic acid (DHA). The visual response to a photon is a retinal cis-trans isomerization. The trans-state is lower in energy; hence, a quantum of energy is released equivalent to the sum of the photon and cis-trans difference. We hypothesize that DHA traps this energy, and the resulting hyperpolarization extracts the energized electron, which depolarizes the membrane and carries a function of the ph...
Retinal, one of several vitamin A compounds serves a vital role in human vision (Tver and Russell, 4...
Modern humans have evolved with a staple source of preformed docosahexaenoic acid (DHA) in the diet....
Docosahexaenoic acid (DHA, 22:6n-3) is highly enriched in the brain mainly in membrane phospholipids...
In George Wald’s Nobel Prize acceptance speech for “discoveries concerning the primary physiological...
Background: Docosahexaenoic acid (DHA) has been the dominant acyl component of the membrane phosphog...
Background: Docosahexaenoic acid (DHA) has been the dominant acyl component of the membrane phosphog...
In our eyes light is absorbed by a polyene molecule called retinal. This molecule contains six doubl...
Retinal photoreceptor cells contain the highest concentration of docosahexaenoic acid (DHA) in our b...
Retinal photoreceptor cells contain the highest concentration of docosahexaenoic acid (DHA) in our b...
Neuronal tissues such as the retina and the brain are characterized by their high content in phospho...
Due to its constant exposure to light and its high oxygen consumption the retina is highly sensitive...
Abstract: The visual system is one of the most energetically demanding systems in the brain. The cur...
Modern humans have evolved with a staple source of preformed docosahexaenoic acid (DHA) in the diet....
Our laboratory is interested in the molecular mechanism ofG protein-mediated signal transduction. We...
International audienceVisual perception by photoreceptors relies on the interaction of incident phot...
Retinal, one of several vitamin A compounds serves a vital role in human vision (Tver and Russell, 4...
Modern humans have evolved with a staple source of preformed docosahexaenoic acid (DHA) in the diet....
Docosahexaenoic acid (DHA, 22:6n-3) is highly enriched in the brain mainly in membrane phospholipids...
In George Wald’s Nobel Prize acceptance speech for “discoveries concerning the primary physiological...
Background: Docosahexaenoic acid (DHA) has been the dominant acyl component of the membrane phosphog...
Background: Docosahexaenoic acid (DHA) has been the dominant acyl component of the membrane phosphog...
In our eyes light is absorbed by a polyene molecule called retinal. This molecule contains six doubl...
Retinal photoreceptor cells contain the highest concentration of docosahexaenoic acid (DHA) in our b...
Retinal photoreceptor cells contain the highest concentration of docosahexaenoic acid (DHA) in our b...
Neuronal tissues such as the retina and the brain are characterized by their high content in phospho...
Due to its constant exposure to light and its high oxygen consumption the retina is highly sensitive...
Abstract: The visual system is one of the most energetically demanding systems in the brain. The cur...
Modern humans have evolved with a staple source of preformed docosahexaenoic acid (DHA) in the diet....
Our laboratory is interested in the molecular mechanism ofG protein-mediated signal transduction. We...
International audienceVisual perception by photoreceptors relies on the interaction of incident phot...
Retinal, one of several vitamin A compounds serves a vital role in human vision (Tver and Russell, 4...
Modern humans have evolved with a staple source of preformed docosahexaenoic acid (DHA) in the diet....
Docosahexaenoic acid (DHA, 22:6n-3) is highly enriched in the brain mainly in membrane phospholipids...