Metabolic models

Metabolic networks are generally better known than other types of cellular networks, and they are therefore well suited for the development of computational models. A range of different techniques can be used to model systems of metabolic reactions, from kinetic methods which seek to represent the exact dynamics of fluxes over time, to constraint-based and structural methods which only consider steady state situations. Altogether these methods have led to important progress in our understanding of cellular functions and how they are regulated by exchanges with the extracellular environment