Add to ORKGSince we entered the post-genome era,the functional analysis of anever-increasing amount of gene information that has been accumulated since the genome era has continued throughout the world. Evolutionary approaches that are mainly based on sequence similarities are efficient tools for the functional analysis of unknown genes or proteins; further,these approaches have highlighted various problems, which cannot be resolved by solely employing these approaches
G-protein coupled receptor (GPCR) is one of the most important protein families for drug target. GPC...
The G-protein coupled receptors - or GPCRs - comprise simultaneously one of the largest and one of t...
Item does not contain fulltextThe 'omics era' (the era of genomics, proteomics, and so forth) is mar...
The , , and proteomes were subjected to BLAST analyses (e-20 cutoff) using our positive interacting ...
An understanding of the functional mechanisms of G-protein-coupled receptors (GPCRs) is very importa...
Numbers in parentheses include redundant protein sequences. A complete list of splice variants and r...
Genetic variations can have positive, negative, or neutral impacts on protein interactions, thus mak...
Covariation between positions in a multiple sequence alignment may reflect structural, functional, a...
For 40 years, molecular biology has used evolutionary approaches as a way to connect macromolecular ...
AbstractRelated proteins with similar biological functions generally share common features, allowing...
<p>Briefly, in the first step, a Genscan dataset was created from the Ensembl February 2004 assembly...
AbstractRelated proteins with similar biological functions generally share common features, allowing...
Until recently, the only computational method available for predicting the function of an uncharacte...
GPCRs comprise a wide and diverse class of eukaryotic transmembrane proteins with well-established p...
We assessed the disease-causing potential of single nucleotide polymorphisms (SNPs) based on a simpl...
G-protein coupled receptor (GPCR) is one of the most important protein families for drug target. GPC...
The G-protein coupled receptors - or GPCRs - comprise simultaneously one of the largest and one of t...
Item does not contain fulltextThe 'omics era' (the era of genomics, proteomics, and so forth) is mar...
The , , and proteomes were subjected to BLAST analyses (e-20 cutoff) using our positive interacting ...
An understanding of the functional mechanisms of G-protein-coupled receptors (GPCRs) is very importa...
Numbers in parentheses include redundant protein sequences. A complete list of splice variants and r...
Genetic variations can have positive, negative, or neutral impacts on protein interactions, thus mak...
Covariation between positions in a multiple sequence alignment may reflect structural, functional, a...
For 40 years, molecular biology has used evolutionary approaches as a way to connect macromolecular ...
AbstractRelated proteins with similar biological functions generally share common features, allowing...
<p>Briefly, in the first step, a Genscan dataset was created from the Ensembl February 2004 assembly...
AbstractRelated proteins with similar biological functions generally share common features, allowing...
Until recently, the only computational method available for predicting the function of an uncharacte...
GPCRs comprise a wide and diverse class of eukaryotic transmembrane proteins with well-established p...
We assessed the disease-causing potential of single nucleotide polymorphisms (SNPs) based on a simpl...
G-protein coupled receptor (GPCR) is one of the most important protein families for drug target. GPC...
The G-protein coupled receptors - or GPCRs - comprise simultaneously one of the largest and one of t...
Item does not contain fulltextThe 'omics era' (the era of genomics, proteomics, and so forth) is mar...