Studies on the Constituents of Aristolochia liukiuensis 2

The chemical constituents in the roots of Aristolochia liukiuensis Hatsusima were examined. Aristolactone (1), mansonone G (3), dehydrooxoperezinone (4), aristololactam D2 (6), 3,4 - methylenedioxy - 8 - methoxyphenanthrene - 1 - carboxylic acid (8), aristolochic acid 2 (10), and aristolochic acid 4 methyl ester (11) were isolated from the roots, in addition to already isolated constituents from the leaves and the stems, such as sitosterol (2), 2-hydroxy-1-methoxy-4,5-dioxo-6,7-dehydroaporphine (5), aristololactam A2 (7), aristolochic acid 1 (9), and sitosterolfl-β-glucoside (12). This is the first report of 4 in natural sources