Experimental procedure and consumption of food and water during chronic PG-LPS infusion in mice.

(A) Lipopolysaccharide derived from Porphylomonas gingivalis (PG-LPS) was administered once daily for 1 week via intraperitoneal injection (i.p.) at a dose of 0.8 mg/kg, dissolved in saline. Age-matched control mice (Control) received an identical volume of saline only. (B) Consumed amounts of food and water were similar among the four groups. P = NS vs. Control). NS, not significantly different from the Control (P > 0.05) by one-way ANOVA followed by the Tukey-Kramer post hoc test. Data shows means ± SD and open circles show individual data. (C) The Control (C), PG-LPS (L), Cap (Ca) and PG-LPS + Cap (L + Ca) groups showed similar body weight at 1 week after the PG-LPS infusion. NS, not significantly different from the Control (P > 0.05) by one-way ANOVA followed by the Tukey-Kramer post hoc test.