(A) Quantitation of organoids numbers in culture with or without CHIR99021(5 μM). (B) Quantitation of organoid sizes at day 5 in culture. Numerical values are in S1 Data. (PDF)</p
(A and B) Representative tumor images (A) and tumor volume at indicated time points (B) in nude mice...
(A) Schematic diagrams showing the domain structures of TcdB and the 2 short fragments derived from ...
(A) Photomicrographs showing immunohistochemistry for PCNA in mouse livers (left) and quantification...
(A) Organoids were seeded in a 48-well plate. TcdBFBD (150 nM) or TcdBmu (150 nM) were added to the ...
(A) Representative images of p53/BRCA1-deficient mouse mammary tumor organoids treated with TcdBFBD ...
(A) Cells dissociated from p53/BRCA1-deficient mammary tumor tissues were resuspended and plated int...
(A, B) Tumor organoid cells from p53/BRAC1-deficient tumor model (A) or C3(1)-Tag model (B) were inj...
(A) FACS analysis using FITC-TcdBFBD and anti-FZD7 antibody showed that primary p53/BRCA1-deficient ...
(A) Left panel: phylogenetic analysis of human FZD proteins [15]; right panel: qRT-PCR analysis of F...
(A) Schematic diagram showing the generation of a p53/BRAC1-deficient breast cancer model by intradu...
(A) Six weeks old female nude mice (Hsd: Athymic Nude-Foxn1nu) were injected (i.p.) with the TcdBFBD...
Tumorsphere number following 3 passages of p53/BRCA1-deficient mammary tumor cells with 150 nM TcdBF...
Figure S1, related to Figure 2. (A) BikDD significantly reduced the CD44+/CD24-population in a patie...
<p>Evaluation of the incidence of tumors in NOD/SCID mice implanted with different numbers of BCSCs ...
<p><b>a</b>, Mice bearing BT483-derived breast cancer xenografts with average tumor size of ∼75 mm<s...
(A and B) Representative tumor images (A) and tumor volume at indicated time points (B) in nude mice...
(A) Schematic diagrams showing the domain structures of TcdB and the 2 short fragments derived from ...
(A) Photomicrographs showing immunohistochemistry for PCNA in mouse livers (left) and quantification...
(A) Organoids were seeded in a 48-well plate. TcdBFBD (150 nM) or TcdBmu (150 nM) were added to the ...
(A) Representative images of p53/BRCA1-deficient mouse mammary tumor organoids treated with TcdBFBD ...
(A) Cells dissociated from p53/BRCA1-deficient mammary tumor tissues were resuspended and plated int...
(A, B) Tumor organoid cells from p53/BRAC1-deficient tumor model (A) or C3(1)-Tag model (B) were inj...
(A) FACS analysis using FITC-TcdBFBD and anti-FZD7 antibody showed that primary p53/BRCA1-deficient ...
(A) Left panel: phylogenetic analysis of human FZD proteins [15]; right panel: qRT-PCR analysis of F...
(A) Schematic diagram showing the generation of a p53/BRAC1-deficient breast cancer model by intradu...
(A) Six weeks old female nude mice (Hsd: Athymic Nude-Foxn1nu) were injected (i.p.) with the TcdBFBD...
Tumorsphere number following 3 passages of p53/BRCA1-deficient mammary tumor cells with 150 nM TcdBF...
Figure S1, related to Figure 2. (A) BikDD significantly reduced the CD44+/CD24-population in a patie...
<p>Evaluation of the incidence of tumors in NOD/SCID mice implanted with different numbers of BCSCs ...
<p><b>a</b>, Mice bearing BT483-derived breast cancer xenografts with average tumor size of ∼75 mm<s...
(A and B) Representative tumor images (A) and tumor volume at indicated time points (B) in nude mice...
(A) Schematic diagrams showing the domain structures of TcdB and the 2 short fragments derived from ...
(A) Photomicrographs showing immunohistochemistry for PCNA in mouse livers (left) and quantification...