Markers of fatal events.

Box plots of the concentration levels for (A) metabolites and (B) lipoprotein parameters (main parameters, calculated figures and main fractions) that have a p-value < 0.05 and a large Cliff’s delta effect size in the comparison between mild, sever and fatal COVID-19 groups. The concentration levels in COVID-19-R subjects are also reported as control values. In each plot, the grey stripe embraces the concentration range in the reference “healthy” population. Colour coding: mild (light red); severe (red); fatal (dark red) COVID-19-R (yellow). * indicates p-value < 0.05: the upper line indicates the statistical significance between all the COVID-19 subjects and the COVID-19-R group; the lower lines indicate statistical significance between pairs of severity groups.