KCNMB1 is a direct transcriptional target of ESR2.

A Luciferase intensity of the reporter gene driven by the KCNMB1 promoter in HCoSMCs. *P B Luciferase activities of the reporter gene driven by a serially truncated/mutated KCNMB1 promoter with ESR2 binding sites indicated in HCoSMCs. **P C ChIP assay for the binding of ESR2 to the KCNMB1 promoter in HCoSMCs. In CHIP and dual luciferase experiments, HCoSMCs were treatment with 50 nmol/l E2.Y-axis shows enrichment with anti-ESR2 antibodies vs. the IgG control. *P < 0.05 vs. anti-IgG, n = 3.