HE (upper panels) or isolectin B4 (lower panels) staining of labyrinth regions.

Placentas were harvested from dams subjected to the: (A, D) Control; (B, E) HFD-P; or (C, F) HFD-PreCP regimen. Maternal red blood cells (non-nucleated) were small and shown clustered, while fetal red blood cells (nucleated) were isolated and denoted by green rings in the upper panels. Maternal sinusoid spaces are indicated by the green arrows, while fetal capillary spaces are indicated by the green triangles. n = 5 placentas from 3 pregnancies evaluated for each staining. Images are shown at 400x magnification.