Add to ORKGUNLABELLED: Recently, there has been an increasing interest in the development and characterization of patient-derived tumor xenograft (PDX) models for cancer research. PDX models mostly retain the principal histologic and genetic characteristics of their donor tumor and remain stable across passages. These models have been shown to be predictive of clinical outcomes and are being used for preclinical drug evaluation, biomarker identification, biologic studies, and personalized medicine strategies. This article summarizes the current state of the art in this field, including methodologic issues, available collections, practical applications, challenges and shortcomings, and future directions, and introduces a European consortium of PDX mode...
Patient-derived xenograft models (PDX) have been extensively used to study the molecular and clinica...
The success of targeted therapies for cancer patients rests on three major components: the right tar...
The ability to create patient derived xenografts (PDXs) has evolved considerably from the breakthrou...
UNLABELLED: Recently, there has been an increasing interest in the development and characterization ...
Recently, there has been an increasing interest in the development and characterization of patient-d...
Recently, there has been an increasing interest in the development and characterization of patient-d...
Recently, there has been an increasing interest in the development and characterization of patient-d...
Basic research and clinical trials are essential components of the process of discovery and developm...
Patient-derived xenografts (PDXs) have emerged as an important platform to elucidate new treatments ...
Patient-derived xenografts (PDXs) have emerged as an important platform to elucidate new treatments ...
Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppr...
Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly supplanting long...
Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly supplanting long...
Patient-derived xenograft models (PDX) have been extensively used to study the molecular and clinica...
The success of targeted therapies for cancer patients rests on three major components: the right tar...
The ability to create patient derived xenografts (PDXs) has evolved considerably from the breakthrou...
UNLABELLED: Recently, there has been an increasing interest in the development and characterization ...
Recently, there has been an increasing interest in the development and characterization of patient-d...
Recently, there has been an increasing interest in the development and characterization of patient-d...
Recently, there has been an increasing interest in the development and characterization of patient-d...
Basic research and clinical trials are essential components of the process of discovery and developm...
Patient-derived xenografts (PDXs) have emerged as an important platform to elucidate new treatments ...
Patient-derived xenografts (PDXs) have emerged as an important platform to elucidate new treatments ...
Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppr...
Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly supplanting long...
Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly supplanting long...
Patient-derived xenograft models (PDX) have been extensively used to study the molecular and clinica...
The success of targeted therapies for cancer patients rests on three major components: the right tar...
The ability to create patient derived xenografts (PDXs) has evolved considerably from the breakthrou...