QTL mapping identifies shared and cross-specific regions associated with piebalding.

Representative QTL results for piebalding in the Cap x Arc (A-B), Hom x Cap (C-D), and OGO x Hom (E-F) crosses. A,C, and E show QTL results for the dorsal right wing. B, D, and F show QTL results for the dorsal body. Lefthand plots illustrate QTL mapping results, with linkage map position on the X-axis and LOD score on the Y-axis. Red lines indicate the threshold for genome-wide statistical significance. Righthand boxplots illustrate the relationship between genotype at the LG15 peak marker and the proportion of white plumage in that body region. In all boxplots, individuals homozygous for the non-piebald founder allele are on the left and individuals homozygous for the piebald founder allele are on the right. Boxes span from the first to third quartile of each data set, with lines indicating the median. Whiskers span up to 1.5x the interquartile range. QTL mapping results for additional body regions are in S3, S4, and S5 Figs.