Medians of gene length L are calculated from the entire genomes set available on the NCBI database. mRNA half-lives t1/2 [18–21], elongation rates p [22–25] and initiation rates α [9, 26] are taken from the literature. is approximated by L/p (unit length is expressed in codons).</p
Abstract Translation efficiency has been mainly studied by ribosome profiling, which only provides a...
Quantitative control of gene expression occurs at multiple levels, including the level of translatio...
Ribosome profiling data report on the distribution of translating ribosomes, at steady-state, with c...
<p>Column description: () transcript length; () number of gene transcripts; () number of proteins pr...
Analysis methods based on simulations and optimization have been previously developed to estimate re...
Analysis methods based on simulations and optimization have been previously developed to estimate re...
Protein abundance is crucial for the majority of genetically regulated cell functions to act properl...
<p>(A) Average elongation speed for a gene decreases as the mean evolutionary conservation of the ge...
Synonymous codon usage and variations in the level of isoaccepting tRNAs exert a powerful selective ...
International audienceProtein synthesis rates are determined, at the translational level, by propert...
The central dogma outlines the flow of information within a cell, whereby a DNA sequence is transcri...
Improved computational modeling of protein translation rates, including better prediction of where t...
Synonymous codon usage and variations in the level of isoaccepting tRNAs exert a powerful selective ...
Although mRNA decay rates are a key determinant of the steady-state concentration for any given mRNA...
In vivo translation-initiation rates of S. cerevisiae transcripts are plotted against the inverse of...
Abstract Translation efficiency has been mainly studied by ribosome profiling, which only provides a...
Quantitative control of gene expression occurs at multiple levels, including the level of translatio...
Ribosome profiling data report on the distribution of translating ribosomes, at steady-state, with c...
<p>Column description: () transcript length; () number of gene transcripts; () number of proteins pr...
Analysis methods based on simulations and optimization have been previously developed to estimate re...
Analysis methods based on simulations and optimization have been previously developed to estimate re...
Protein abundance is crucial for the majority of genetically regulated cell functions to act properl...
<p>(A) Average elongation speed for a gene decreases as the mean evolutionary conservation of the ge...
Synonymous codon usage and variations in the level of isoaccepting tRNAs exert a powerful selective ...
International audienceProtein synthesis rates are determined, at the translational level, by propert...
The central dogma outlines the flow of information within a cell, whereby a DNA sequence is transcri...
Improved computational modeling of protein translation rates, including better prediction of where t...
Synonymous codon usage and variations in the level of isoaccepting tRNAs exert a powerful selective ...
Although mRNA decay rates are a key determinant of the steady-state concentration for any given mRNA...
In vivo translation-initiation rates of S. cerevisiae transcripts are plotted against the inverse of...
Abstract Translation efficiency has been mainly studied by ribosome profiling, which only provides a...
Quantitative control of gene expression occurs at multiple levels, including the level of translatio...
Ribosome profiling data report on the distribution of translating ribosomes, at steady-state, with c...