Lamina glia are specialised to perform immune-related functions.

(A) UMAP of the adult optic lobe glia colour-coded for lamina (maroon) and “general” (medulla, lobula, and lobula plate; blue) glial clusters that were included in the GO analysis in (B). Note that the chiasm glia cluster (dark grey) and non-homeostatic clusters belonging to multiplets (light grey) were excluded from the analysis in (B). (B) GO enrichment analysis for biological processes of the lamina glia compared to other (general) optic lobe glia shown as a heatmap. We used a dendrogram to cluster GO terms into groups that were defined by a super-term. The scale indicates the negative log of the FDR. The data underlying this figure can be found in S7 Data and on GitHub at https://github.com/VilFernandesLab/2022_DrosophilaGlialAtlas. FDR, false discovery rate; GO, Gene Ontology; UMAP, uniform manifold approximation and projection.