Putting either CTA1-GFP (A) or the untagged CTA1 (B) back to the endogenous locus in the cta1Δ background restored the resistance to H2O2 compared with the wild type strain. Each strain was treated at the indicated concentrations of H2O2 for 2 hours, then spotted onto YPD plates and incubated at 30°C for 48 hours (A) and 20hrs (B). (C) ASR in the wild type, CTA1 complement (cta1::CTA1) and cta1Δ strains. The experiment was conducted similarly as in Fig 3 for wild type and cta1Δ strains. Concentrations of H2O2 were calibrated to achieve a similar basal survival rates (open circles, Kruskal-Wallis rank sum test for differences among the three groups P = 0.38). ASR-scores for the three strains are (with 95% CI and Wilcoxon signed-rank test P-v...
Serial dilutions of log-phase HR-cultures were plated onto enriched blood agar (5μg/ml hemin supplem...
<p>(<b>A</b>) Strain AP1 is more virulent in tg mice that express human complement inhibitors. BALB/...
<p>(A) Survival after a 30-min stress with 2 mM H<sub>2</sub>O<sub>2</sub> for the parental (HM1070,...
We restored RIM15 at the endogenous locus on the rim15Δ background and compared its ASR effect to th...
To test if pre-inducing CTA1 is sufficient to provide ASR for H2O2, we replaced the endogenous CTA1 ...
(A) CTA1 mRNA levels were assayed using qRT-PCR following 45 minutes of either 1.5 mM H2O2, phosphat...
(A) Basal survival rates (r) at different H2O2 concentrations in C. glabrata and S. cerevisiae were ...
(A) (Left) Deleting cta1 and the OSR TF, yap1, had no defect on survival under phosphate starvation,...
(A, B) Samples were serially diluted, plated in duplicate on TY Tau plates and incubated either in a...
<p>The percentage of resistance to bile (0.2%, 0.5%, 0.75%, 1.0%, and 2.0%) was calculated by compar...
Data is reported as a ratio of average OD (tx) to average starting OD (t0) in each survival curve (n...
<p>(A) Hydrogen peroxide resistance of pre-adapted Xcc cells. Exponential phase cultures of Xcc wild...
<p>The growth and/or survival of hvKP1 was assessed at 0, 3, 6, and 24 hours in 100% human ascites s...
(A) qRT-PCR analysis of steady state argT and katE mRNA levels during mid-exponential growth in LB (...
<p>(A) Representative acquired H<sub>2</sub>O<sub>2</sub> resistance assays for wild-type YPS163 and...
Serial dilutions of log-phase HR-cultures were plated onto enriched blood agar (5μg/ml hemin supplem...
<p>(<b>A</b>) Strain AP1 is more virulent in tg mice that express human complement inhibitors. BALB/...
<p>(A) Survival after a 30-min stress with 2 mM H<sub>2</sub>O<sub>2</sub> for the parental (HM1070,...
We restored RIM15 at the endogenous locus on the rim15Δ background and compared its ASR effect to th...
To test if pre-inducing CTA1 is sufficient to provide ASR for H2O2, we replaced the endogenous CTA1 ...
(A) CTA1 mRNA levels were assayed using qRT-PCR following 45 minutes of either 1.5 mM H2O2, phosphat...
(A) Basal survival rates (r) at different H2O2 concentrations in C. glabrata and S. cerevisiae were ...
(A) (Left) Deleting cta1 and the OSR TF, yap1, had no defect on survival under phosphate starvation,...
(A, B) Samples were serially diluted, plated in duplicate on TY Tau plates and incubated either in a...
<p>The percentage of resistance to bile (0.2%, 0.5%, 0.75%, 1.0%, and 2.0%) was calculated by compar...
Data is reported as a ratio of average OD (tx) to average starting OD (t0) in each survival curve (n...
<p>(A) Hydrogen peroxide resistance of pre-adapted Xcc cells. Exponential phase cultures of Xcc wild...
<p>The growth and/or survival of hvKP1 was assessed at 0, 3, 6, and 24 hours in 100% human ascites s...
(A) qRT-PCR analysis of steady state argT and katE mRNA levels during mid-exponential growth in LB (...
<p>(A) Representative acquired H<sub>2</sub>O<sub>2</sub> resistance assays for wild-type YPS163 and...
Serial dilutions of log-phase HR-cultures were plated onto enriched blood agar (5μg/ml hemin supplem...
<p>(<b>A</b>) Strain AP1 is more virulent in tg mice that express human complement inhibitors. BALB/...
<p>(A) Survival after a 30-min stress with 2 mM H<sub>2</sub>O<sub>2</sub> for the parental (HM1070,...