International audienceNewly determined crystal structures suggest that the membrane-binding C2 domains of blood coagulation cofactors Va and VIIIa bind anionic phospholipids through protruding solvent-exposed hydrophobic residues, aided by a crown of positively charged residues and by specific hydrogen-bonding side chains
Coagulation cofactor factor Va (FVa) is an essential component of the prothrombinase complex, and is...
AbstractFactor VIII (FVIII), a plasma glycoprotein, is an essential cofactor in the blood coagulatio...
Haemostasis is a highly regulated, fundamental, physiological process featuring numerous peripheral ...
International audienceNewly determined crystal structures suggest that the membrane-binding C2 domai...
AbstractNewly determined crystal structures suggest that the membrane-binding C2 domains of blood co...
The large, multifunctional proteins Factors V and VIII are cofactors in the coagulation cascade and ...
Blood coagulation factor Va serves an indispensable role in hemostasis as cofactor for the serine pr...
Rapid and controlled clot formation is achieved through sequential activation of circulating serine ...
Blood coagulation factor VIII is an essential cofactor in the mammalian blood-clotting cascade. FVII...
The C-terminal C domains of activated coagulation factor VIII (FVIIIa) are essential to membrane bin...
Background: Blood coagulation factor (F) Va is the essential protein cofactor to the serine protease...
In the blood coagulation pathway the zymogen factor X (FX) is converted to its enzymatic form (FXa) ...
Blood coagulation factor VIII (fVIII) functions as a cofactor in the blood coagulation cascade for p...
The large, multifunctional proteins Factors V and VIII are cofactors in the coagulation cascade and ...
SummaryThe GLA domain, a common membrane-anchoring domain of several serine protease coagulation fac...
Coagulation cofactor factor Va (FVa) is an essential component of the prothrombinase complex, and is...
AbstractFactor VIII (FVIII), a plasma glycoprotein, is an essential cofactor in the blood coagulatio...
Haemostasis is a highly regulated, fundamental, physiological process featuring numerous peripheral ...
International audienceNewly determined crystal structures suggest that the membrane-binding C2 domai...
AbstractNewly determined crystal structures suggest that the membrane-binding C2 domains of blood co...
The large, multifunctional proteins Factors V and VIII are cofactors in the coagulation cascade and ...
Blood coagulation factor Va serves an indispensable role in hemostasis as cofactor for the serine pr...
Rapid and controlled clot formation is achieved through sequential activation of circulating serine ...
Blood coagulation factor VIII is an essential cofactor in the mammalian blood-clotting cascade. FVII...
The C-terminal C domains of activated coagulation factor VIII (FVIIIa) are essential to membrane bin...
Background: Blood coagulation factor (F) Va is the essential protein cofactor to the serine protease...
In the blood coagulation pathway the zymogen factor X (FX) is converted to its enzymatic form (FXa) ...
Blood coagulation factor VIII (fVIII) functions as a cofactor in the blood coagulation cascade for p...
The large, multifunctional proteins Factors V and VIII are cofactors in the coagulation cascade and ...
SummaryThe GLA domain, a common membrane-anchoring domain of several serine protease coagulation fac...
Coagulation cofactor factor Va (FVa) is an essential component of the prothrombinase complex, and is...
AbstractFactor VIII (FVIII), a plasma glycoprotein, is an essential cofactor in the blood coagulatio...
Haemostasis is a highly regulated, fundamental, physiological process featuring numerous peripheral ...
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