There is increasing recognition that osteoarthritis (OA) is a complex disease involving the whole synovial joint, rather than the articular cartilage alone, however its aetiology and pathogenesis is not understood. Our initial studies revealed elevated turnover of bone and ligament collagen in human and mouse OA, respectively. To investigate the relative appearance of pathology in cartilage, bone and ligament, we studied the progression of spontaneous OA in the Dunkin-Hartley (DH) guinea pig knee, and compared with age-matched control Bristol Strain 2 (BS2) knees. The classical radiographic OA score of the DH knees compared to BS2 knees was 2-fold higher at 24 weeks of age. The patella perimeter and subchondral bone density was significantl...
AbstractObjective To examine the collagens in cruciate ligaments of young Dunkin-Hartley guinea pigs...
Osteoarthritis (OA) is a degenerative joint diseases characterised by pain, immobility, cartilage de...
Objective: To examine the collagens in cruciate ligaments of young Dunkin-Hartley guinea pigs, to ...
There is increasing recognition that osteoarthritis (OA) is a complex disease involving the whole sy...
Osteoarthritis has an unknown aetiology, and tissue samples from early stage human osteoarthritis ti...
Objective. The influence of the cruciate ligaments in spontaneous osteoarthritis (OA) is not underst...
SummaryObjectiveThis study aimed to investigate the spatial and temporal subchondral bone change of ...
The course of primary osteoarthrosis (OA) in Hartley guinea pigs, which spontaneously develop OA in ...
Osteoarthritis (OA) - an unspecific term for late joint destruction-is one of the most common causes...
Osteoarthritis (OA) is a progression of degenerative joint disease which can cause disability. Previ...
Osteoarthritis (OA) is a prevalent joint disease without a cure and leading cause of disability worl...
Osteoarthritis (OA) is the most common joint disorder, characterised by focal loss of cartilage and ...
Osteoarthritis (OA) is the most common joint disorder, characterised by focal loss of cartilage and ...
AbstractObjective To examine the collagens in cruciate ligaments of young Dunkin-Hartley guinea pigs...
Osteoarthritis (OA) is a degenerative joint diseases characterised by pain, immobility, cartilage de...
Objective: To examine the collagens in cruciate ligaments of young Dunkin-Hartley guinea pigs, to ...
There is increasing recognition that osteoarthritis (OA) is a complex disease involving the whole sy...
Osteoarthritis has an unknown aetiology, and tissue samples from early stage human osteoarthritis ti...
Objective. The influence of the cruciate ligaments in spontaneous osteoarthritis (OA) is not underst...
SummaryObjectiveThis study aimed to investigate the spatial and temporal subchondral bone change of ...
The course of primary osteoarthrosis (OA) in Hartley guinea pigs, which spontaneously develop OA in ...
Osteoarthritis (OA) - an unspecific term for late joint destruction-is one of the most common causes...
Osteoarthritis (OA) is a progression of degenerative joint disease which can cause disability. Previ...
Osteoarthritis (OA) is a prevalent joint disease without a cure and leading cause of disability worl...
Osteoarthritis (OA) is the most common joint disorder, characterised by focal loss of cartilage and ...
Osteoarthritis (OA) is the most common joint disorder, characterised by focal loss of cartilage and ...
AbstractObjective To examine the collagens in cruciate ligaments of young Dunkin-Hartley guinea pigs...
Osteoarthritis (OA) is a degenerative joint diseases characterised by pain, immobility, cartilage de...
Objective: To examine the collagens in cruciate ligaments of young Dunkin-Hartley guinea pigs, to ...