Structurally defined α-Tetralol-Based chiral hypervalent iodine reagents

A novel class of chiral hypervalent iodine reagents containing an α-tetralol-scaffold is being introduced. Iodine triacetate is employed in a key-step as highly selective and efficient iodinating reagent for a short and convenient synthesis of iodine(III) derivatives. Solid state X-ray analyses offer valuable structural information while reactivities and stereoselectivities are investigated in three model reactions