Enzymatically oxidized phospholipids (eoxPLs) are formed through regulated processes by which eicosanoids or prostaglandins are attached to phospholipids (PLs) in immune cells. These eoxPLs comprise structurally diverse families of biomolecules with potent bioactivities, and they have important immunoregulatory roles in both health and disease. The formation of oxPLs through enzymatic pathways and their signaling capabilities are emerging concepts. This paradigm is changing our understanding of eicosanoid, prostaglandin, and PL biology in health and disease. eoxPLs have roles in cellular events such as ferroptosis, apoptosis, and blood clotting and diseases such as arthritis, diabetes, and cardiovascular disease. They are increasingly recog...
Inflammation represents a powerful innate immune response that defends tissue homeostasis. However, ...
Oxidized PLs (OxPLs) generated in health and disease are now recognized as important mediators of ce...
AbstractLipid peroxidation occurs in the context of many physiological processes but is greatly incr...
Enzymatically oxidized phospholipids (eoxPLs) are formed through regulated processes by which eicosa...
Exposure of biological membranes to reactive oxygen species creates a complex mixture of distinct ox...
High fidelity and effective adaptive changes of the cell and tissue metabolism to changing environme...
Phospholipids are of critical importance in mammalian cell biology, both through providing a permeab...
Oxidized phospholipids (OxPL) were originally discovered as by-products and mediators of chronic inf...
Phospholipids comprise a large body of lipids that define cells and organelles by forming membrane ...
Oxidized phospholipids (oxPLs) that can be generated either enzymatically or non-enzymatically are f...
Phospholipids (PLs) are found in all cell types and are required for structural support and cell act...
Enzymatically oxidized lipids are a specific group of biomolecules that function as key signaling me...
# The Author(s) 2013. This article is published with open access at Springerlink.com Abstract Oxidiz...
Polyunsaturated fatty acids are precursors of multiple pro-and anti-inflammatory molecules generated...
Blood coagulation functions as part of the innate immune system by preventing bacterial invasion and...
Inflammation represents a powerful innate immune response that defends tissue homeostasis. However, ...
Oxidized PLs (OxPLs) generated in health and disease are now recognized as important mediators of ce...
AbstractLipid peroxidation occurs in the context of many physiological processes but is greatly incr...
Enzymatically oxidized phospholipids (eoxPLs) are formed through regulated processes by which eicosa...
Exposure of biological membranes to reactive oxygen species creates a complex mixture of distinct ox...
High fidelity and effective adaptive changes of the cell and tissue metabolism to changing environme...
Phospholipids are of critical importance in mammalian cell biology, both through providing a permeab...
Oxidized phospholipids (OxPL) were originally discovered as by-products and mediators of chronic inf...
Phospholipids comprise a large body of lipids that define cells and organelles by forming membrane ...
Oxidized phospholipids (oxPLs) that can be generated either enzymatically or non-enzymatically are f...
Phospholipids (PLs) are found in all cell types and are required for structural support and cell act...
Enzymatically oxidized lipids are a specific group of biomolecules that function as key signaling me...
# The Author(s) 2013. This article is published with open access at Springerlink.com Abstract Oxidiz...
Polyunsaturated fatty acids are precursors of multiple pro-and anti-inflammatory molecules generated...
Blood coagulation functions as part of the innate immune system by preventing bacterial invasion and...
Inflammation represents a powerful innate immune response that defends tissue homeostasis. However, ...
Oxidized PLs (OxPLs) generated in health and disease are now recognized as important mediators of ce...
AbstractLipid peroxidation occurs in the context of many physiological processes but is greatly incr...