We investigate star formation and dust heating in the compact far-infrared (FIR) bright sources detected in the Herschel maps of M83. We use the source extraction code GETSOURCES to detect and extract sources in the FIR, as well as their photometry in the mid-infrared and Hα. By performing infrared spectral energy distribution fitting and applying an Hα-based star formation rate (SFR) calibration, we derive the dust masses and temperatures, SFRs, gas masses and star formation efficiencies (SFEs). The detected sources lie exclusively on the spiral arms and represent giant molecular associations, with gas masses and sizes of 106–108 M⊙ and 200–300 pc, respectively. The inferred parameters show little to no radial dependence and there is only ...