Background: The mitochondrial protein translocase of inner mitochondrial membrane 17 homolog A (TIMM17A) has been identified as a biomarker of breast cancer. The present study aimed to investigate the biological role of TIMM17A in human breast cancer cells. Materials and Methods: Anti-TIMM17A transgenes were stably transfected into MDA MB-231 and MCF-7 breast cancer cell lines. The impact of TIMM17A knock-down on cell migration and invasion were evaluated using the respective cell models. Results: Reducing the expression of TIMM17A in breast cancer cells resulted in reduction of cell migration using electric cell-substrate impedance sensing. It was also found that reduction of TIMM17A expression resulted in reduction of cell invasion compar...
(EN) Tumours are heterogeneous and consist of multiple populations of cells. The population of cells...
2014-04-28Transmembrane protein TMEM 56 was first identified as an IKK‐associated protein by mass sp...
In vitro analyses of basement membrane invasiveness employing Matrigel (a murine tumor extract rich ...
Background: The mitochondrial protein translocase of inner mitochondrial membrane 17 homolog A (TIMM...
Background Mitochondrial dysfunction can be associated with genomic instability and has been impl...
BackgroundTranslocase of inner mitochondrial membrane 17A (TIMM17A) is overexpressed in breast cance...
Yue Zhao,1 Kuiyuan Song,1 Yong Zhang,2 Hongtao Xu,1 Xiupeng Zhang,1 Liang Wang,1 Chuifeng Fan,1 Guiy...
Mitochondria play important roles in cancer progression and have emerged as viable targets for cance...
[[abstract]]BackgroundThe inner membrane mitochondrial protein (IMMT) is a central unit of the mitoc...
The present study is aimed at studying the gene for TIMP-3, a mammalian tissue inhibitor, by constru...
<div><p>Despite advances in screening and treatment over the past several years, breast cancer remai...
MPV17 is described as a mitochondrial inner membrane channel. Although its function remains elusive,...
An estrogen receptor–negative variant of the MCF-7 breast cancer cell line, TMX2-28, was used as a m...
MAP17 (PDZK1IP1) is a small protein regulating inflammation and tumor progression, upregulated in a ...
MAP17 (PDZK1IP1) is a small protein regulating inflammation and tumor progression, upregulated in a ...
(EN) Tumours are heterogeneous and consist of multiple populations of cells. The population of cells...
2014-04-28Transmembrane protein TMEM 56 was first identified as an IKK‐associated protein by mass sp...
In vitro analyses of basement membrane invasiveness employing Matrigel (a murine tumor extract rich ...
Background: The mitochondrial protein translocase of inner mitochondrial membrane 17 homolog A (TIMM...
Background Mitochondrial dysfunction can be associated with genomic instability and has been impl...
BackgroundTranslocase of inner mitochondrial membrane 17A (TIMM17A) is overexpressed in breast cance...
Yue Zhao,1 Kuiyuan Song,1 Yong Zhang,2 Hongtao Xu,1 Xiupeng Zhang,1 Liang Wang,1 Chuifeng Fan,1 Guiy...
Mitochondria play important roles in cancer progression and have emerged as viable targets for cance...
[[abstract]]BackgroundThe inner membrane mitochondrial protein (IMMT) is a central unit of the mitoc...
The present study is aimed at studying the gene for TIMP-3, a mammalian tissue inhibitor, by constru...
<div><p>Despite advances in screening and treatment over the past several years, breast cancer remai...
MPV17 is described as a mitochondrial inner membrane channel. Although its function remains elusive,...
An estrogen receptor–negative variant of the MCF-7 breast cancer cell line, TMX2-28, was used as a m...
MAP17 (PDZK1IP1) is a small protein regulating inflammation and tumor progression, upregulated in a ...
MAP17 (PDZK1IP1) is a small protein regulating inflammation and tumor progression, upregulated in a ...
(EN) Tumours are heterogeneous and consist of multiple populations of cells. The population of cells...
2014-04-28Transmembrane protein TMEM 56 was first identified as an IKK‐associated protein by mass sp...
In vitro analyses of basement membrane invasiveness employing Matrigel (a murine tumor extract rich ...
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