Four experiments examined the role of the cholinergic projections from the septum and vertical limb nucleus of the diagonal band of Broca (VDB) in acquisition and performance of a conditional visual discrimination. In experiments 1-3, excitotoxic lesions were made of the septum and VDB in rats using quisqualic acid, which resulted in significant reductions in ChAT activity in the hippocampus and cingulate cortex, but with no effects on cortical monoamines. In experiment 1, there were significant impairments in acquisition of the conditional discrimination, which did not result from motivational impairments. Experiment 2 repeated these results with lesion parameters, which produced variable effects on hippocampal and cingulate ChAT activity....
The effectiveness of a recently developed immunotoxin, 192 IgG-saporin, was evaluated for making sel...
To date, research using rodent models has primarily dealt with the visual aspects of attention, whil...
that quisqualic acid lesions of the nucleus basalis magnocellularis (NBM), although producing large ...
Four experiments examined the role of the cholinergic projections from the septum and vertical limb ...
In rats, nonspecific mechanical or neurotoxic lesions of the septum impair spatial memory in, e.g., ...
192IgG-saporin (SAP) was used to selectively destroy cholinergic neurons in the rostral basal forebr...
Cholinergic neurons in the basal forebrain innervate discrete regions of the cortical mantle, bestow...
The cholinergic neurons of the basal forebrain, which project to cortex, the thalamic reticular nucl...
The importance of cholinergic neurons projecting from the medial septum (MS) of the basal forebrain ...
This study tested the hypothesis that septal cholinergic lesions impair acquisition of a delayed mat...
The attention directed to environmental stimuli can be modified by experience. For example, preexpos...
Four experiments examined effects of quinolinic acid-induced lesions of the anterior cingulate, post...
The role of forebrain cholinergic projections in place navigation learning was assessed in two exper...
Feature binding refers to the fundamental challenge of the brain to integrate sensory information re...
Our ability to foresee and shape biologically important events relies on a combination of visuospati...
The effectiveness of a recently developed immunotoxin, 192 IgG-saporin, was evaluated for making sel...
To date, research using rodent models has primarily dealt with the visual aspects of attention, whil...
that quisqualic acid lesions of the nucleus basalis magnocellularis (NBM), although producing large ...
Four experiments examined the role of the cholinergic projections from the septum and vertical limb ...
In rats, nonspecific mechanical or neurotoxic lesions of the septum impair spatial memory in, e.g., ...
192IgG-saporin (SAP) was used to selectively destroy cholinergic neurons in the rostral basal forebr...
Cholinergic neurons in the basal forebrain innervate discrete regions of the cortical mantle, bestow...
The cholinergic neurons of the basal forebrain, which project to cortex, the thalamic reticular nucl...
The importance of cholinergic neurons projecting from the medial septum (MS) of the basal forebrain ...
This study tested the hypothesis that septal cholinergic lesions impair acquisition of a delayed mat...
The attention directed to environmental stimuli can be modified by experience. For example, preexpos...
Four experiments examined effects of quinolinic acid-induced lesions of the anterior cingulate, post...
The role of forebrain cholinergic projections in place navigation learning was assessed in two exper...
Feature binding refers to the fundamental challenge of the brain to integrate sensory information re...
Our ability to foresee and shape biologically important events relies on a combination of visuospati...
The effectiveness of a recently developed immunotoxin, 192 IgG-saporin, was evaluated for making sel...
To date, research using rodent models has primarily dealt with the visual aspects of attention, whil...
that quisqualic acid lesions of the nucleus basalis magnocellularis (NBM), although producing large ...