Signal generation and detection systems (excluding homogeneous assays)

This chapter reviews the more common and most interesting labelling and signal detection methods, including radioactive, enzyme (colorimetric, fluorometric, chemiluminescent, enhanced chemiluminescent), direct fluorescent, time-resolved fluorescent, direct chemiluminescent, phosphorescent, micro- and nanoparticle, streptavidin/avidin-biotin and protein A. There are sections on amplification strategies, multiple analytes and miniaturization (including microarrays)