Fluoride is known to alter mineralization within bone, although the mechanism for its action is unclear. An important stage in the formation of mineralized tissues is the remodeling of the osteoid, facilitating mineral deposition. Using a bone mineralizing culture system derived from rat femur washes, this study investigated the influence of fluoride on MMP expression at a developmental stage relating to the onset of mineralization. Bone cells cultured in the absence of fluoride synthesized an active form of a 45-kD MMP, which was immunoreactive with an antibody to human MMP-1 (although full characterization of this MMP was not achieved), trace levels of an MMP immunoreactive with anti-MMP-3, and a 66-kD proteolytic species. Incubation in 1...
INTRODUCTION: A variation in bone response to fluoride (F(-)) exposure has been attributed to geneti...
PosterBackground: Periodontal diseases are inflammatory conditions of the tooth supporting tissues. ...
Enamel fluorosis is characterised by increased porosity and a delay in the removal of enamel matrix ...
Fluoride is known to alter mineralization within bone, although the mechanism for its action is uncl...
Objective. This study investigated the influence of fluoride levels on the temporal synthesis of bon...
In an effort to assess the effects of F on overall bone metabolism, cultures of osteoblastic cells i...
Genetic factors influence the effects of fluoride (F) on amelogenesis and bone homeostasis but the u...
This study evaluated the influence of fluoride on cell viability and activity of matrix metalloprote...
ABSTRACT: Over the past two decades, fluoride effects on osteoclasts have been evaluated; however, i...
This study aimed to characterize fluoride-induced alterations in dentin mineralization within a dent...
The femurs from rats given 120 ppm fluoride in their drinking water for 4 weeks were examined with h...
This dissertation was designed to test the hypothesis that fluoride-stimulated osteoblast proliferat...
Abstract: Fluoride as a supplement can affect the structural integrity of bone. Fluoride that is inc...
The work described considers the effects on calcified tissues of those concentrations of fluoride wh...
Mechanisms underlying the association between atherosclerosis and periodontitis are not defined. Mat...
INTRODUCTION: A variation in bone response to fluoride (F(-)) exposure has been attributed to geneti...
PosterBackground: Periodontal diseases are inflammatory conditions of the tooth supporting tissues. ...
Enamel fluorosis is characterised by increased porosity and a delay in the removal of enamel matrix ...
Fluoride is known to alter mineralization within bone, although the mechanism for its action is uncl...
Objective. This study investigated the influence of fluoride levels on the temporal synthesis of bon...
In an effort to assess the effects of F on overall bone metabolism, cultures of osteoblastic cells i...
Genetic factors influence the effects of fluoride (F) on amelogenesis and bone homeostasis but the u...
This study evaluated the influence of fluoride on cell viability and activity of matrix metalloprote...
ABSTRACT: Over the past two decades, fluoride effects on osteoclasts have been evaluated; however, i...
This study aimed to characterize fluoride-induced alterations in dentin mineralization within a dent...
The femurs from rats given 120 ppm fluoride in their drinking water for 4 weeks were examined with h...
This dissertation was designed to test the hypothesis that fluoride-stimulated osteoblast proliferat...
Abstract: Fluoride as a supplement can affect the structural integrity of bone. Fluoride that is inc...
The work described considers the effects on calcified tissues of those concentrations of fluoride wh...
Mechanisms underlying the association between atherosclerosis and periodontitis are not defined. Mat...
INTRODUCTION: A variation in bone response to fluoride (F(-)) exposure has been attributed to geneti...
PosterBackground: Periodontal diseases are inflammatory conditions of the tooth supporting tissues. ...
Enamel fluorosis is characterised by increased porosity and a delay in the removal of enamel matrix ...