Recent evidence suggests that hippocampal changes are present in vascular cognitive impairment but their importance and relationship with ischaemic mechanisms remain controversial. To investigate these issues we performed MRI and cognitive assessment in a large cohort (n = 144) of patients with CADASIL, a hereditary small vessel disease and model of pure vascular cognitive impairment. Dementia status was ascribed according to DSM-IV and global cognitive function assessed with the Minimental State Examination (MMSE) and Mattis Dementia Rating Scale (MDRS). Hippocampalvolume (HV) correlated with age (r = −0.33, p < 0.001), brain volume (r = 0.39, p < 0.001) and lacunar lesion volume (r = −0.23, p = 0.008), but not white matter lesions or micr...
Background:Research in older adults with subjective cognitive decline (SCD) has mainly focused on Al...
In the elderly, the high prevalence of Alzheimer's disease neuropathology presents a major challenge...
INTRODUCTION[|]The presence of vascular lesions may be a risk factor for neurodegenerative diseases....
Recent evidence suggests that hippocampal changes are present in vascular cognitive impairment but t...
CADASIL is an arteriopathy caused by mutations of the Notch3 gene. White matter hyperintensities (WM...
Abstract—CADASIL is an early onset small vessel disease and genetic variant of pure subcortical isch...
BACKGROUND AND OBJECTIVE: CADASIL is the most common monogenic form of stroke and early onset dement...
OBJECTIVE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopath...
Dementia is a syndrome with cognitive decline as a prominent feature. MCI is similarly a syndrome of...
Although there is evidence for correlations between disability and magnetic resonance imaging (MRI) ...
Patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalop...
Vascular risk factors affect cerebral blood flow (CBF) and cerebral vascular reactivity, contributin...
BACKGROUND AND PURPOSE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leuk...
\ua9 2020 The Authors. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoe...
BACKGROUND AND PURPOSE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leuk...
Background:Research in older adults with subjective cognitive decline (SCD) has mainly focused on Al...
In the elderly, the high prevalence of Alzheimer's disease neuropathology presents a major challenge...
INTRODUCTION[|]The presence of vascular lesions may be a risk factor for neurodegenerative diseases....
Recent evidence suggests that hippocampal changes are present in vascular cognitive impairment but t...
CADASIL is an arteriopathy caused by mutations of the Notch3 gene. White matter hyperintensities (WM...
Abstract—CADASIL is an early onset small vessel disease and genetic variant of pure subcortical isch...
BACKGROUND AND OBJECTIVE: CADASIL is the most common monogenic form of stroke and early onset dement...
OBJECTIVE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopath...
Dementia is a syndrome with cognitive decline as a prominent feature. MCI is similarly a syndrome of...
Although there is evidence for correlations between disability and magnetic resonance imaging (MRI) ...
Patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalop...
Vascular risk factors affect cerebral blood flow (CBF) and cerebral vascular reactivity, contributin...
BACKGROUND AND PURPOSE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leuk...
\ua9 2020 The Authors. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoe...
BACKGROUND AND PURPOSE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leuk...
Background:Research in older adults with subjective cognitive decline (SCD) has mainly focused on Al...
In the elderly, the high prevalence of Alzheimer's disease neuropathology presents a major challenge...
INTRODUCTION[|]The presence of vascular lesions may be a risk factor for neurodegenerative diseases....