Mixed acetals as new precursors for selenium electrophiles

A wide range of precursors for selenium electrophiles is already known, but the requirements for the development of polymer-bound selenium reagents are different. Herein we report mixed acetals as new precursor molecules for the synthesis of selenium electophiles under very mild reaction conditions. The use of (MeOCH2Se)2 allows a very fast access to these mixed acetals. Chiral precursor molecules can be synthesized as well and employed in efficient stereoselective selenenylation reactions