Genetic and self‐perceived ancestries in Argentina: Beyond the three‐hybrid model

Ruderman, Anahí
Luisi, Pierre
Paschetta, Carolina Andrea
Teodoroff, Tamara Alejandra
Perez, Luis Orlando
de Azevedo, Soledad
Trujillo Jiménez, Magda Alexandra
Navarro, Jose Pablo
Morales, Arturo Leonardo
Pazos, Bruno Alfredo
Gonzalez-Jose, Rolando
Ramallo, Virginia

Open link

Publication date

February 2023

DOI

10.1002/ajpa.24702

Publisher

John Wiley & Sons

Journal

2692-7691

Abstract

Objectives: The increased availability of genome-wide data allows capturing the fine genetic structure of present days populations. Here we analyze the genetic ancestry at a fine scale of an Argentinean Patagonia population to understand the origins beyond the three-hybrid model, and to compare these results with volunteers' self-perceived ancestry in a broad context encompassed by historical and familiar information. Materials and Methods: We compare high-throughput genotyping data for 92 individuals that we generated to data sets from the literature by applying fully haplotype-based methods to examine patterns of human population substructure. The volunteers filled out a semi-structured questionnaire, including questions about their histo...