IntroductionThe midgut epithelium functions as tissue for nutrient uptake as well as physical barrier against pathogens. Additionally, it responds to pathogen contact by production and release of various factors including antimicrobial peptides, similar to the systemic innate immune response. However, if such a response is restricted to a local stimulus or if it appears in response to a systemic infection, too is a rather underexplored topic in insect immunity. We addressed the role of the midgut and the role of systemic immune tissues in the defense against gut-borne and systemic infections, respectively.MethodsManduca sexta larvae were challenged with DAP-type peptidoglycan bacteria – Bacillus thuringiensis for local gut infection and Esc...
<p>Mosquitoes that transmit many deadly infectious diseases also need to keep fighting against many ...
Background: Insects thriving on nutritionally poor habitats have integrated mutualistic intracellula...
A robust but tightly regulated system of innate gut immunity is required for maintaining gut homeost...
IntroductionThe midgut epithelium functions as tissue for nutrient uptake as well as physical barrie...
The fruit fly Drosophila is an excellent model to study the response of different immunocompetent or...
Female Culicoides sonorensis midges (Diptera: Ceratopogonidae) are vectors of pathogens that impact ...
Background: Persistent infections with mutualistic intracellular bacteria (endosymbionts) are well r...
Insects and mammals share evolutionary conserved innate immune responses to maintain intestinal home...
Background: Lepidoptera insects have a novel development process comprising several metamorphic stag...
Insects and mammals share evolutionary conserved innate immune responses to maintain intestinal home...
Insects and mammals share evolutionary conserved innate immune responses to maintain intestinal home...
Communities of symbiotic microorganisms that colonize the gastrointestinal tract play an important r...
The dipteran Hermetia illucens (Diptera: Stratiomyidae), also known as black soldier fly, is a promi...
The fruit fly Drosophila is an excellent model to study the response of different immunocompetent or...
For the vast majority of vector borne parasites the ability to overcome the insect midgut defences i...
<p>Mosquitoes that transmit many deadly infectious diseases also need to keep fighting against many ...
Background: Insects thriving on nutritionally poor habitats have integrated mutualistic intracellula...
A robust but tightly regulated system of innate gut immunity is required for maintaining gut homeost...
IntroductionThe midgut epithelium functions as tissue for nutrient uptake as well as physical barrie...
The fruit fly Drosophila is an excellent model to study the response of different immunocompetent or...
Female Culicoides sonorensis midges (Diptera: Ceratopogonidae) are vectors of pathogens that impact ...
Background: Persistent infections with mutualistic intracellular bacteria (endosymbionts) are well r...
Insects and mammals share evolutionary conserved innate immune responses to maintain intestinal home...
Background: Lepidoptera insects have a novel development process comprising several metamorphic stag...
Insects and mammals share evolutionary conserved innate immune responses to maintain intestinal home...
Insects and mammals share evolutionary conserved innate immune responses to maintain intestinal home...
Communities of symbiotic microorganisms that colonize the gastrointestinal tract play an important r...
The dipteran Hermetia illucens (Diptera: Stratiomyidae), also known as black soldier fly, is a promi...
The fruit fly Drosophila is an excellent model to study the response of different immunocompetent or...
For the vast majority of vector borne parasites the ability to overcome the insect midgut defences i...
<p>Mosquitoes that transmit many deadly infectious diseases also need to keep fighting against many ...
Background: Insects thriving on nutritionally poor habitats have integrated mutualistic intracellula...
A robust but tightly regulated system of innate gut immunity is required for maintaining gut homeost...