(a) Graphic demonstrating expression pattern for late upregulated (red) and downregulated (blue) genes along our timepoints. (b-d) Top 10 enriched KEGG pathway terms including p-value and # of genes found as DEGs in the NTR-rod (b), NTR-bipolar (c) or from shared DEGs across both paradigms (d). (e-g) Top 10 enriched Gene Ontology pathway terms including fold enrichment and false discovery rate in the NTR-rod (e), NTR-bipolar (f) or from shared DEGs across both paradigms (g, only 7 terms enriched in this group). (h-i) Unsupervised gene networks produced from ingenuity pathway analysis for DEGs in the NTR-rod (h) and NTR-bipolar (i) paradigm. Orange indicates upregulated gene/pathway term while blue indicates downregulated.</p
The top 15 GO enrichment terms and pathways are shown. (A) Biological process, (B) molecular functio...
The top 15 GO enrichment terms and pathways are shown. (A) Biological process, (B) molecular functio...
(A) Heatmap constructed using 199 upregulated and 441 downregulated genes in exhausted T-cells. Sign...
(a) Curve demonstrating expression pattern for early upregulated (red) and downregulated (blue) gene...
(a) Curve demonstrating expression pattern for early upregulated (red) and downregulated (blue) gene...
(a) Curve demonstrating expression pattern for early upregulated (red) and downregulated (blue) gene...
<p>Red bars represent the persistently upregulated KEGG pathway enrichment significance levels, and ...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
Pathway analysis encompassing the top 150 meta-DEGs: (a) Representative network model of interaction...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
The top 15 GO enrichment terms and pathways are shown. (A) Biological process, (B) molecular functio...
The top 15 GO enrichment terms and pathways are shown. (A) Biological process, (B) molecular functio...
(A) Heatmap constructed using 199 upregulated and 441 downregulated genes in exhausted T-cells. Sign...
(a) Curve demonstrating expression pattern for early upregulated (red) and downregulated (blue) gene...
(a) Curve demonstrating expression pattern for early upregulated (red) and downregulated (blue) gene...
(a) Curve demonstrating expression pattern for early upregulated (red) and downregulated (blue) gene...
<p>Red bars represent the persistently upregulated KEGG pathway enrichment significance levels, and ...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
Pathway analysis encompassing the top 150 meta-DEGs: (a) Representative network model of interaction...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
(a) Volcano plot showing the identified up (orange) and down (blue) DEGs in both NTR-rod and NTR-bip...
The top 15 GO enrichment terms and pathways are shown. (A) Biological process, (B) molecular functio...
The top 15 GO enrichment terms and pathways are shown. (A) Biological process, (B) molecular functio...
(A) Heatmap constructed using 199 upregulated and 441 downregulated genes in exhausted T-cells. Sign...