Bisulfite sequencing of the <i>Apc</i> promoter region in small intestinal tumors of B6/B6-Chr18<sup>MSM</sup>-F1 <i>Apc</i><sup><i>Min/+</i></sup> mice.
- Daisuke Iizuka (455515)
- Megumi Sasatani (610227)
- Atsuko Ishikawa (11272944)
- Kazuhiro Daino (203837)
- Tokuhisa Hirouchi (17137967)
- Kenji Kamiya (610230)
Publication date
October 2023
DOIAbstract
Methylation status of the 93 CpG dinucleotides in the promoter region of Apc. Each circle represents a CpG site in the genomic DNA sequence and each row of circles represents the analysis of a single cloned allele. Closed circles: methylated CpG dinucleotides; open circles: unmethylated CpG dinucleotides. Bisulfite efficiency averaged 98.5 ± 1.33% for CpG island 1 and 98.8 ± 1.23% for CpG island 2 in all samples examined.</p
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