AbstractThe interaction between cladding panels and the main structure is a crucial point to assess the seismic response, and above all the structural safety, of RC precast industrial building. In the past, connections were often designed to allow construction tolerances and to accommodate both thermal and wind-induced displacements. The lack of specific details to allow relative in-plane displacements between cladding panels and the main structure often led to the participation of cladding panels in the structure seismic-resistant system with consequent connection failures. In the last decades, a lot of experimental tests were performed to investigate the in-plane performance of panel connections, and some design recommendations have been ...