Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor.
- Veronica Mutti
- Jessica Mingardi
- Massimo Gennarelli
- Adele Guglielmi
- Cristina Missale
- Federica Bono
- Alessandro Barbon
- Chiara Fiorentini
- Alessandra Minelli
- Giovanna Piovani
DOIAbstract
Abstract Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs line exhibits a normal karyotype, expresses stemness markers and displays the differentiation capacity into the three germ layers. This human iPSCs line can be used as healthy control in disease modelling studies
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