Magister Scientiae - MSC (Biochemistry)Proteins play an important role in cells, as the morphology, function and activities of the cell depend on the proteins they express. The key to understanding how different proteins function lies in an understanding of the molecular structure. The overall aim of this thesis was the determination of the structure of DWNN domains. This thesis described the preparation of samples of human DWNN suitable for structural analysis by nuclear magnetic resonance spectroscopy (NMR), as well as NMR analysis.South Afric
X-ray crystallography is a tool for determining the structures of proteins and protein-ligand comple...
[[abstract]]Understanding the functions of the vast number of proteins encoded in many genomes that ...
Dyskerin is a conserved nucleolar protein. Several related genetic diseases are caused by defects in...
Magister Scientiae - MScThe cellular levels of a number of proteins have been found to be regulated ...
<p><b>Copyright information:</b></p><p>Taken from "DWNN, a novel ubiquitin-like domain, implicates R...
The ubiquitin fold acts as a signaling modulator associated with regulating, trafficking, and degrad...
Gene expression is a highly regulated process in our eukaryotic cells. To accomplish tight and dynam...
<p><b>Copyright information:</b></p><p>Taken from "DWNN, a novel ubiquitin-like domain, implicates R...
Drosophila Raf (D-Raf) is an orthologue of Human B-Raf. D-Raf may have two splice variants, a short ...
NMR spectroscopy has recently become a promising field for protein characterization and dynamic stud...
Abstract This paper describes efforts of the structural genomics project in the nuclear magnetic res...
WWP2, a NEDD4 E3 ubiquitin ligase, contains four WW domains which display a preference for binding p...
<p><b>Copyright information:</b></p><p>Taken from "DWNN, a novel ubiquitin-like domain, implicates R...
SH3 domains are excellent models for probing folding and protein interactions. This thesis describes...
Structural genomics, the determination of protein structures on a genome-wide scale, is still in its...
X-ray crystallography is a tool for determining the structures of proteins and protein-ligand comple...
[[abstract]]Understanding the functions of the vast number of proteins encoded in many genomes that ...
Dyskerin is a conserved nucleolar protein. Several related genetic diseases are caused by defects in...
Magister Scientiae - MScThe cellular levels of a number of proteins have been found to be regulated ...
<p><b>Copyright information:</b></p><p>Taken from "DWNN, a novel ubiquitin-like domain, implicates R...
The ubiquitin fold acts as a signaling modulator associated with regulating, trafficking, and degrad...
Gene expression is a highly regulated process in our eukaryotic cells. To accomplish tight and dynam...
<p><b>Copyright information:</b></p><p>Taken from "DWNN, a novel ubiquitin-like domain, implicates R...
Drosophila Raf (D-Raf) is an orthologue of Human B-Raf. D-Raf may have two splice variants, a short ...
NMR spectroscopy has recently become a promising field for protein characterization and dynamic stud...
Abstract This paper describes efforts of the structural genomics project in the nuclear magnetic res...
WWP2, a NEDD4 E3 ubiquitin ligase, contains four WW domains which display a preference for binding p...
<p><b>Copyright information:</b></p><p>Taken from "DWNN, a novel ubiquitin-like domain, implicates R...
SH3 domains are excellent models for probing folding and protein interactions. This thesis describes...
Structural genomics, the determination of protein structures on a genome-wide scale, is still in its...
X-ray crystallography is a tool for determining the structures of proteins and protein-ligand comple...
[[abstract]]Understanding the functions of the vast number of proteins encoded in many genomes that ...
Dyskerin is a conserved nucleolar protein. Several related genetic diseases are caused by defects in...