Types of paramagnetic contrast agents in MRI

Magnetna kontrastna sredstva su tvari koje se koriste u medicinskoj dijagnostici kako bi se poboljšala vidljivost i kontrast na slikama dobivenim magnetnom rezonancom (MR). MR je napredna neinvazivna tehnika slikanja koja koristi jak magnetski pol i radiofrekventne valove za generiranje detaljnih trodimenzionalnih slika unutrašnjih tkiva i organa u tijelu. Magnetna kontrastna sredstva su paramagnetske supstance koje sadrže atome s nesparenim elektronima. Kada se primijene u tijelu pacijenta prije MR pregleda, reagiraju s magnetskim poljem MR uređaja i stvaraju lokalne magnetske momente. Ti momenti mijenjaju lokalno magnetsko polje, što rezultira povećanim kontrastom na MR slici. Ova poboljšana vidljivost omogućuje medicinskim stručnjacima bolju identifikaciju i procjenu bolesti, oštećenja ili drugih abnormalnosti. Koriste se u različitim kliničkim scenarijima, kao što su otkrivanje tumora, dijagnostika krvnih žila, praćenje bolesti mozga i lezija koštane srži. Ovisno o vrsti pregleda, mogu se primijeniti intravenski, oralno ili lokalno. Važno je napomenuti da imaju potencijalne rizike i nuspojave. Neke osobe mogu biti alergične na ove tvari, pa je važno provesti anamnezu i provjeriti povijest alergija prije primjene. Magnetna kontrastna sredstva su važan alat u dijagnostičkoj radiologiji, posebno u MR slikanju. Ona pomažu poboljšati kontrast na MR slikama i omogućuju precizniju dijagnostiku i praćenje bolesti.Magnetic contrast agents are substances used in medical diagnostics to improve visibility and contrast in magnetic resonance (MR) images. MR is an advanced non-invasive imaging technique that uses a strong magnetic pole and radio frequency waves to generate detailed three-dimensional images of internal tissues and organs in the body. Magnetic contrast agents are paramagnetic substances that contain atoms with unpaired electrons. When applied to the patient's body before an MR examination, they react with the magnetic field of the MR device and generate local magnetic moments. These moments change the local magnetic field, which results in increased contrast in the MR image. This improved visibility allows medical professionals to better identify and assess disease, damage or other abnormalities. They are used in various clinical scenarios, such as tumor detection, blood vessel diagnostics, monitoring of brain diseases and bone marrow lesions. Depending on the type of examination, they can be administered intravenously, orally or locally. It is important to note that they have potential risks and side effects. Some people may be allergic to these substances, so it is important to take an anamnesis and check the history of allergies before use. Magnetic contrast agents are an important tool in diagnostic radiology, especially in MR imaging. They help to improve contrast on MR images and enable more accurate diagnosis and disease monitoring