Changes in plasma lipid and glutatione-peroxidase activity due to aerobic bicycle exercise

The purpose of this study was to investigate the effects of regular aerobic exercise on plasma lipid levels and GSH-px activity in human male subjects. An aerobic exercise group (5) and a rugby football player group (6) perfomed 30 minutes of aerobic exercise on a bicycle ergometer. Plasma NEFA, LPO concentration and plasma GSH-px activity were measured before, immediately after and 30 min. after the exercise. The results were as follows : 1) Pre-exercise levels of plasma NEFA. LPO and GSH-px in the regular aerobic exercise group were lower than those of the rugby football player group. 2) In the regular aerobic exercise group, plasma NEFA Ievels were increased, but plasma LPO and GSH-px levels were showed no significant change as a result of the 30 min. bicycle ergometer exercise. In the rugby football player group, slight elevations of plasma NEFA and LPO were observed, but GSH-px was unchanged immediately after the exercise. 3) In the regular aerobic exercise group, plasma NEFA Ievels had decreased at 30 min. after the exercise, but they were higher than the pre-exercise levels. Plasma LPO Ievels were not changed, but at 30 min. after the exercise plasma GSH-px activity had increased compared with immediately after the exercise. In the rugby football player group, plasma NEFA Ievels were not changed. Plasma LPO was increased, but plasma GSH-px activity was unchanged at 30 min. after the exercise compared with immediately after the exercise. These results indicate that regular aerobic exercise may induce enzymatic adaptation with higher GSH-px activity and maintain a higher level of plasma LPO with exercise at a lower level