Add to ORKGInhibition of dipeptidyl peptidase-IV (DPP-IV) is used as a means to regulate post-prandial serum glucose in type 2 diabetics. The effect of drug (Sitagliptin®)/peptide and binary peptide mixtures on DPP-IV inhibition was studied using an isobole approach. Five peptides (Ile-Pro-Ile-Gln-Tyr, Trp-Lys, Trp-Pro, Trp-Arg and Trp-Leu), having DPP-IV half maximum inhibitory concentration values (IC₅₀)<60 μM and reported to act through different inhibition mechanisms, were investigated. The dose response relationship of Sitagliptin : peptide (1:0, 0:1, 1:852, 1:426 and 1:1704 on a molar basis) and binary Ile-Pro-Ile-Gln-Tyr : peptide (1:0, 0:1, 1:1, 1:2 and 2:1 on a molar basis) mixtures for DPP-IV inhibition was characterised. Isobolographic anal...
Dipeptidyl-peptidase IV (DPP-IV) plays an essential role in glucose metabolism by inactivating incre...
Recent investigations have focused on food-derived peptides as novel natural inhibitors of dipeptidy...
peer-reviewedInhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the increti...
Inhibition of dipeptidyl peptidase-IV (DPP-IV) is used as a means to regulate post-prandial serum gl...
peer-reviewedInhibition of dipeptidyl peptidase-IV (DPP-IV) is used as a means to regulate post-pran...
Inhibition of the enzyme dipeptidyl-peptidase IV (DPP-IV) is a promising approach for managing hyper...
Since drug based inhibition of dipeptidyl peptidase IV (DPP-IV) is employed in type 2 (T2D) diabetes...
Since drug based inhibition of dipeptidyl peptidase IV (DPP-IV) is employed in type 2 (T2D) diabetes...
Inhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the incretin effect duri...
Inhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the incretin effect duri...
Diabetes is a chronic metabolic disorder which leads to high blood sugar levels over a prolonged per...
<p>Inhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the incretin effect d...
peer-reviewedSince drug based inhibition of dipeptidyl peptidase IV (DPP-IV) is employed in type 2 (...
Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) are of increasing interest to both diabeto...
The prevalence of type 2 diabetes mellitus (T2DM) is increasing and it is estimated that by 2030 app...
Dipeptidyl-peptidase IV (DPP-IV) plays an essential role in glucose metabolism by inactivating incre...
Recent investigations have focused on food-derived peptides as novel natural inhibitors of dipeptidy...
peer-reviewedInhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the increti...
Inhibition of dipeptidyl peptidase-IV (DPP-IV) is used as a means to regulate post-prandial serum gl...
peer-reviewedInhibition of dipeptidyl peptidase-IV (DPP-IV) is used as a means to regulate post-pran...
Inhibition of the enzyme dipeptidyl-peptidase IV (DPP-IV) is a promising approach for managing hyper...
Since drug based inhibition of dipeptidyl peptidase IV (DPP-IV) is employed in type 2 (T2D) diabetes...
Since drug based inhibition of dipeptidyl peptidase IV (DPP-IV) is employed in type 2 (T2D) diabetes...
Inhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the incretin effect duri...
Inhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the incretin effect duri...
Diabetes is a chronic metabolic disorder which leads to high blood sugar levels over a prolonged per...
<p>Inhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the incretin effect d...
peer-reviewedSince drug based inhibition of dipeptidyl peptidase IV (DPP-IV) is employed in type 2 (...
Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) are of increasing interest to both diabeto...
The prevalence of type 2 diabetes mellitus (T2DM) is increasing and it is estimated that by 2030 app...
Dipeptidyl-peptidase IV (DPP-IV) plays an essential role in glucose metabolism by inactivating incre...
Recent investigations have focused on food-derived peptides as novel natural inhibitors of dipeptidy...
peer-reviewedInhibition of dipeptidyl peptidase IV (DPP-IV) may be exploited to maintain the increti...