Submerged culture fermentation of the Basidiomycete fungus Ganoderma lucidum for biomass formation

Apprendix with raw dataThe aim of the present study was to investigate a range of bioprocess strategies aimed at the achievement of maximum biomass yield in submerged cultivation of the Basidiomycete, Ganoderma lucidum. Although there had been previous studies into cultivation of G, lucidum, these had been almost exclusively centred round maximisation of the medically interesting polysaccharide, EPS. The present work is focused on the development of fermentation strategies to achieve this aim, which was a central interest of the sponsor. Additionally, to investigate the process physiology of these complex cultures to help improve the relatively poor, understanding of the bioprocessing of this Basidiomycete fungus and to understand the influence of process variables during submerged cultivation of G. lucidum on growth, polysaccharide production and substrate consumption.The aim of the present study was to investigate a range of bioprocess strategies aimed at the achievement of maximum biomass yield in submerged cultivation of the Basidiomycete, Ganoderma lucidum. Although there had been previous studies into cultivation of G, lucidum, these had been almost exclusively centred round maximisation of the medically interesting polysaccharide, EPS. The present work is focused on the development of fermentation strategies to achieve this aim, which was a central interest of the sponsor. Additionally, to investigate the process physiology of these complex cultures to help improve the relatively poor, understanding of the bioprocessing of this Basidiomycete fungus and to understand the influence of process variables during submerged cultivation of G. lucidum on growth, polysaccharide production and substrate consumption