Research Progress of Laboratory Diagnosis of TB

Early, rapid, and accurate identification of Mycobacterium tuberculosis is crucial to the treatment and management of the disease, and laboratory diagnosis is an important means for its diagnosis, treatment, and prevention control. Common methods include pathogenic methods based on bacterial smear and culture, molecular methods based on polymerase chain reaction (PCR), immunological methods such as tuberculin skin test and gamma-interferon (IFN-γ) release test, and the latest emergence of molecular methods, such as Xpert MTB/RIF and CRISPR technology have provided new perspectives for TB diagnosis. This review focuses on the main research advances in laboratory diagnosis of TB