The treatment of lung infection in the context of cystic fibrosis (CF) is limited by a biofilm mode of growth of pathogenic organisms. When compared to planktonically grown bacteria, bacterial biofilms can survive extremely high levels of antimicrobials. Within the lung, bacterial biofilms are aggregates of microorganisms suspended in a matrix of self-secreted proteins within the sputum. These structures offer both physical protection from antibiotics as well as a heterogeneous population of metabolically and phenotypically distinct bacteria. The bacteria themselves and the components of the extracellular matrix, in addition to the signaling pathways that direct their behaviour, are all potential targets for therapeutic intervention discuss...
Pseudomonas aeruginosa, Staphylococcus aureus, Burkholderia cepacia and Stenotrophomonas maltophilia...
THESIS 10820P. aeruginosa infection is one of the main causes of lung function decline in patients w...
The prognosis of patients with cystic fibrosis (CF) has improved dramatically over the last three de...
The ultimate aim of any antimicrobial treatment is a better infection outcome for the patient. Here,...
AbstractChronic P. aeruginosa infection is characterized by production of mucoid alginate and format...
The global rise in antibiotic resistance is a significant problem facing healthcare professionals. I...
Concurrently to conventional bacterial pathogens, unusual microbes are emerging from cystic fibrosis...
International audienceBiofilms formed by pathogenic bacteria and fungi are associated with a wide ra...
Distinct availabilities of oxygen, nutrients and antibiotics in the cystic fibrosis (CF) airways hav...
Concurrent to conventional bacterial pathogens, unusual microbes are emerging from cystic fibrosis (...
Concurrent to conventional bacterial pathogens, unusual microbes are emerging from cystic fibrosis (...
poster abstractCystic Fibrosis is a genetic disease caused by a mutation which inhibits the proper t...
Recent evidence indicates that Pseudomonas aeruginosa residing as biofilms in airway mucus of cystic...
Patients suffering from cystic fibrosis (CF) are commonly affected by chronic Pseudomonas aeruginosa...
Copyright © 2014 Susana P. Lopes et al.This is an open access article distributed under the Creative...
Pseudomonas aeruginosa, Staphylococcus aureus, Burkholderia cepacia and Stenotrophomonas maltophilia...
THESIS 10820P. aeruginosa infection is one of the main causes of lung function decline in patients w...
The prognosis of patients with cystic fibrosis (CF) has improved dramatically over the last three de...
The ultimate aim of any antimicrobial treatment is a better infection outcome for the patient. Here,...
AbstractChronic P. aeruginosa infection is characterized by production of mucoid alginate and format...
The global rise in antibiotic resistance is a significant problem facing healthcare professionals. I...
Concurrently to conventional bacterial pathogens, unusual microbes are emerging from cystic fibrosis...
International audienceBiofilms formed by pathogenic bacteria and fungi are associated with a wide ra...
Distinct availabilities of oxygen, nutrients and antibiotics in the cystic fibrosis (CF) airways hav...
Concurrent to conventional bacterial pathogens, unusual microbes are emerging from cystic fibrosis (...
Concurrent to conventional bacterial pathogens, unusual microbes are emerging from cystic fibrosis (...
poster abstractCystic Fibrosis is a genetic disease caused by a mutation which inhibits the proper t...
Recent evidence indicates that Pseudomonas aeruginosa residing as biofilms in airway mucus of cystic...
Patients suffering from cystic fibrosis (CF) are commonly affected by chronic Pseudomonas aeruginosa...
Copyright © 2014 Susana P. Lopes et al.This is an open access article distributed under the Creative...
Pseudomonas aeruginosa, Staphylococcus aureus, Burkholderia cepacia and Stenotrophomonas maltophilia...
THESIS 10820P. aeruginosa infection is one of the main causes of lung function decline in patients w...
The prognosis of patients with cystic fibrosis (CF) has improved dramatically over the last three de...