Analysis by response surface methodology of gold nanoparticles obtained by green chemical reduction using aqueous coffee pulp extract (Coffea arabica)

Green synthesis of gold nanoparticles using an aqueous coffee (Coffea arabica) pulp extract as a reducing agent was achieved and analyzed by response surface methodology, given the diverse applicability of these nanoparticles containing a wide range of phenolic compounds from the coffee pulp extract. Three factors (precursor concentration, reducing agent concentration, and reaction time) were considered and their combined effects on the maximum intensity (MA), particle size (d), and particle density (N) were analyzed. An opposing effect between the precursor and reducing agent was observed during synthesis because while the precursor increased d and diminished N, the reducing agent diminished d and increased N. These effects were observed simultaneously through the response surfaces of d and N. This methodology allowed the synthesis of nanoparticles with an average particle size between 5–22 nm and N around 2.9x10The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author