Add to ORKGObesity among youth with bipolar disorder (BD) is associated with greater illness severity. In adult BD, obesity is associated with neurostructural differences. We examined this topic for the first time in youth. T1-weighted images of 40 BD and 48 psychiatrically healthy controls (HC) were processed using FreeSurfer to derive cortical region of interest (ROI) volumes/cortical thickness for frontal lobe (FL), prefrontal cortex (PFC), and orbitofrontal cortex (OFC), as well as subcortical ROI volumes for amygdala and hippocampus. Our results show that there was a significant BMI-by-group interaction effect on FL and OFC volumes. In the BD group only, BMI was significantly negatively associated with OFC volume, as well as FL, OFC, and PFC cort...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here we aimed t...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often associated wi...
Abstract Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often asso...
Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often associated wi...
BACKGROUND: Obesity is highly prevalent and disabling, especially in individuals with severe mental ...
AIMS: Rates of obesity have reached epidemic proportions, especially among people with psychiatric d...
Up to 75% of people with bipolar disorder (BD) are overweight or obese, and these patients suffer mo...
Background Individuals with bipolar disorder (BD) have a higher prevalence of obesity and metabolic ...
Cortical thickness (CT) and brain-derived neurotrophic factor (BDNF) were widely investigated in bip...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Background Fronto-limbic structural brain abnormalities have been reported in patients with bipolar ...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here we aimed t...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here we aimed t...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often associated wi...
Abstract Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often asso...
Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often associated wi...
BACKGROUND: Obesity is highly prevalent and disabling, especially in individuals with severe mental ...
AIMS: Rates of obesity have reached epidemic proportions, especially among people with psychiatric d...
Up to 75% of people with bipolar disorder (BD) are overweight or obese, and these patients suffer mo...
Background Individuals with bipolar disorder (BD) have a higher prevalence of obesity and metabolic ...
Cortical thickness (CT) and brain-derived neurotrophic factor (BDNF) were widely investigated in bip...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Background Fronto-limbic structural brain abnormalities have been reported in patients with bipolar ...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here we aimed t...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here we aimed t...
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understo...