Right Ventricular Systolic Pressure and not Left Ventricular Systolic Function is Associated with Renal Insufficiency in Patients with Chronic Heart Failure

Background: Patients with heart failure (HF) with concomitant kidney disease have poor prognosis. Recent studies conducted in patients with acute HF showed that increased filling pressure causes renal vein hypertension resulting to renal insufficiency. Accordingly, this study aimed to correlate right ventricular systolic pressure (RVSP) to renal function in patients with chronic stable HF. Methods: Serum creatinine (sCr) and estimated glomerular filtration rate (eGFR) were correlated with RVSP, N-terminal-pro-Brain Natriuretic Peptide (NT-proBNP), and left ventricular ejection fraction (LVEF) in patients with chronic stable HF.Results: Mean age 70 ± 13 years, 72% male. Mean systolic blood pressure 121 ± 20 mmHg. Both eGFR and sCr correlated with RVSP (p = 0.004 and p = 0.005, respectively) and NT-proBNP (pM.Sc