The two classes of cytokines Th1 and Th2 determine the type of immune response elicited. The Th2 immune response is associated with successful pregnancy. Brucellosis is an intracellular bacterium that elicits the Th1 response and is known to cause spontaneous abortion in mammalian species. This study sought to determine if Brucella infection causes spontaneous abortion by causing the circulating cytokine profile be Th1 dominant during pregnancy. Fortyeight Swiss white mice were used in this murine model and the S19 strain of Brucella abortus was used in as the infective agent. Pregnant mice in the test group were injected intraperitoneally with 105-8 CFU of Brucella and cytokine profile evaluated over the three trimesters of pregnancy. Pr...
Brucellosis is an infection caused by the bacterium Brucella abortus, which is a concern for both th...
BALB/c mice infected with Brucella abortus strain 2308 have 10-fold higher levels of bacteria during...
<p>Five wild-type or IL-10 KO mice were infected i.p. with a dose of 10<sup>6</sup> CFU of <i>B. abo...
The two classes of cytokines Th1 and Th2 determine the type of immune response elicited. The Th2 imm...
Research on Brucella pathogenesis has focused primarily on its ability to cause persistent intracell...
Research on Brucella pathogenesis has focused primarily on its ability to cause persistent intracell...
Stealthy intracellular bacterial pathogens are known to establish persistent and sometimes life-long...
Abortion and reproductive failures induced by Brucella are the main symptoms of animal brucellosis. ...
Abortion and reproductive failures induced by Brucella are the main symptoms of animal brucellosis. ...
Brucella abortus-infected mice to soluble Cytokine response of T-cell subsets fro
Abstract Background The mechanisms of abortion induced by bacterial infection are largely unknown. I...
Neospora caninum is an obligate intracellular protozoan parasite which is efficiently transmitted tr...
Chlamydophila abortus (C. abortus) is the aetiological agent of ovine enzootic abortion (OEA). The h...
Neospora caninum is an obligate intracellular protozoan parasite which is efficiently transmitted tr...
Chlamydophila abortus (C. abortus) is the aetiological agent of ovine enzootic abortion (OEA). The h...
Brucellosis is an infection caused by the bacterium Brucella abortus, which is a concern for both th...
BALB/c mice infected with Brucella abortus strain 2308 have 10-fold higher levels of bacteria during...
<p>Five wild-type or IL-10 KO mice were infected i.p. with a dose of 10<sup>6</sup> CFU of <i>B. abo...
The two classes of cytokines Th1 and Th2 determine the type of immune response elicited. The Th2 imm...
Research on Brucella pathogenesis has focused primarily on its ability to cause persistent intracell...
Research on Brucella pathogenesis has focused primarily on its ability to cause persistent intracell...
Stealthy intracellular bacterial pathogens are known to establish persistent and sometimes life-long...
Abortion and reproductive failures induced by Brucella are the main symptoms of animal brucellosis. ...
Abortion and reproductive failures induced by Brucella are the main symptoms of animal brucellosis. ...
Brucella abortus-infected mice to soluble Cytokine response of T-cell subsets fro
Abstract Background The mechanisms of abortion induced by bacterial infection are largely unknown. I...
Neospora caninum is an obligate intracellular protozoan parasite which is efficiently transmitted tr...
Chlamydophila abortus (C. abortus) is the aetiological agent of ovine enzootic abortion (OEA). The h...
Neospora caninum is an obligate intracellular protozoan parasite which is efficiently transmitted tr...
Chlamydophila abortus (C. abortus) is the aetiological agent of ovine enzootic abortion (OEA). The h...
Brucellosis is an infection caused by the bacterium Brucella abortus, which is a concern for both th...
BALB/c mice infected with Brucella abortus strain 2308 have 10-fold higher levels of bacteria during...
<p>Five wild-type or IL-10 KO mice were infected i.p. with a dose of 10<sup>6</sup> CFU of <i>B. abo...