Nodular amelanotic melanoma

  • Nalamwar, Rashmi
  • Kharkar, Vidya
  • Mahajan, Sunanda
  • Chikhalkar, Sidhhi
  • Khopkar, Uday
Publication date
December 2010
Publisher
University of Toronto Medical Journal

Abstract

We report a case of 65-year-old male patient who presented with multiple erythematous papules coalescing to form a nodular mass over posterior aspect of right thigh of six months duration. His general and systemic examinations were within normal range except for right inguinal lymphadenopathy. Biopsy from the lesion was done, which showed diffuse infiltrate of nests of atypical melanocytes extending upto reticular dermis. Malignant cells were positive for S100 and human melanin black 45(HMB 45). Hence, a diagnosis of amelanotic melanoma (AM) - Clarke level IV and TNM stage III was reached. MRI of involved leg showed fungating soft tissue mass in the posterolateral aspect of right thigh and metastatic right inguinal adenopathy. Fine needle a...

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