Add to ORKGStroke is a leading cause of disability in the world, for which there currently is no effective treatment. One potential method for treating stroke is to stimulate the endogenous neural stem/progenitor cells (NSPCs) in the subventricular zone (SVZ) of adult brain to replace the tissue lost during stroke. Two growth factors that have shown promise in eliciting functional repair in rodent models of stroke are epidermal growth factor (EGF) and erythropoietin (EPO). However, there is a significant challenge in delivering protein drugs in a minimally invasive yet effective manner. In this thesis, a minimally invasive polymer-based system is developed to control the sequential release of EGF followed by EPO. This system comprises of a hyaluronan-...
The hematopoietic growth factor erythropoietin (EPO) and its neuroprotective, but not hematopoietic,...
Traumatic spinal cord injury (SCI) is a devastating condition for which there is no effective clinic...
Targeting the brain cavity formed by an ischemic stroke is appealing for many regenerative treatment...
Stroke is a leading cause of disability in the world, for which there currently is no effective trea...
Until the early 1990s it was common belief that the adult brain did not possess the capacity to chan...
Until the early 1990s it was common belief that the adult brain did not possess the capacity to chan...
Stroke is the leading cause of disability and the fifth-leading cause of death in the United States....
Stroke is the leading cause of adult disability in the United States. The severe and highly reactive...
Stroke is the leading cause of adult disability in the United States. The severe and highly reactive...
Introduction: Ischemic stroke is caused by reduced blood supply and leads to loss of brain function....
Stroke is the leading cause of adult disability. Systemic delivery of candidate neural repair therap...
Although strokes are the leading cause of adult disability, the leading treatment after initial inte...
Stroke is a devastating disease for which no clinical treatment exists to regenerate lost tissue. St...
Current clinical trials for hemorrhagic stroke use minimally invasive surgery plus tissue plasminoge...
The hematopoietic growth factor erythropoietin (EPO) and its neuroprotective, but not hematopoietic,...
The hematopoietic growth factor erythropoietin (EPO) and its neuroprotective, but not hematopoietic,...
Traumatic spinal cord injury (SCI) is a devastating condition for which there is no effective clinic...
Targeting the brain cavity formed by an ischemic stroke is appealing for many regenerative treatment...
Stroke is a leading cause of disability in the world, for which there currently is no effective trea...
Until the early 1990s it was common belief that the adult brain did not possess the capacity to chan...
Until the early 1990s it was common belief that the adult brain did not possess the capacity to chan...
Stroke is the leading cause of disability and the fifth-leading cause of death in the United States....
Stroke is the leading cause of adult disability in the United States. The severe and highly reactive...
Stroke is the leading cause of adult disability in the United States. The severe and highly reactive...
Introduction: Ischemic stroke is caused by reduced blood supply and leads to loss of brain function....
Stroke is the leading cause of adult disability. Systemic delivery of candidate neural repair therap...
Although strokes are the leading cause of adult disability, the leading treatment after initial inte...
Stroke is a devastating disease for which no clinical treatment exists to regenerate lost tissue. St...
Current clinical trials for hemorrhagic stroke use minimally invasive surgery plus tissue plasminoge...
The hematopoietic growth factor erythropoietin (EPO) and its neuroprotective, but not hematopoietic,...
The hematopoietic growth factor erythropoietin (EPO) and its neuroprotective, but not hematopoietic,...
Traumatic spinal cord injury (SCI) is a devastating condition for which there is no effective clinic...
Targeting the brain cavity formed by an ischemic stroke is appealing for many regenerative treatment...