Add to ORKGThe reading frame hypothesis has been proposed to explain the molecular basis of two allelic forms of muscular dystrophies, Duchenne/Becker muscular dystrophy (D/BMD). To evaluate the hypothesis in Indian D/BMD patients, we analyzed deletion of dystrophin exons in 147 DMD and 19 BMD patients. Our studies showed deviation of more than 30% from the reading frame hypothesis in DMD patients (47/147). The present results implicate a need to reevaluate the reading frame hypothesis
Background: Becker muscular dystrophy (BMD) is caused by mutations in the dystrophin gene with varia...
Deletions giving rise to Duchenne muscular dystrophy (DMD) and the less severe Becker muscular dystr...
DMD gene exons duplications account for up to 5-10 % of Duchenne (DMD) and up to 5-19% of Becker (BM...
The reading frame hypothesis has been proposed to explain the molecular basis of two allelic forms o...
The molecular basis of two allelic forms of muscular dystrophy, Duchenne (DMD) and Becker (BMD), has...
International audienceMutations of the dystrophin DMD gene, essentially deletions of one or several ...
Duchenne (DMD) and Becker muscular dystrophies (BMD) are X-linked recessive neuromuscular disorders ...
Duchenne and Becker muscular dystrophy severity depends upon the nature and location of the DMD gene...
Duchenne muscular dystrophy is caused by mutations in the DMD gene that disrupt the open reading fra...
Muscular dystrophies have historically been characterised according to clinical criteria, however in...
Background: Becker muscular dystrophy (BMD) is caused by mutations in the dystrophin gene with varia...
Deletions giving rise to Duchenne muscular dystrophy (DMD) and the less severe Becker muscular dystr...
DMD gene exons duplications account for up to 5-10 % of Duchenne (DMD) and up to 5-19% of Becker (BM...
The reading frame hypothesis has been proposed to explain the molecular basis of two allelic forms o...
The molecular basis of two allelic forms of muscular dystrophy, Duchenne (DMD) and Becker (BMD), has...
International audienceMutations of the dystrophin DMD gene, essentially deletions of one or several ...
Duchenne (DMD) and Becker muscular dystrophies (BMD) are X-linked recessive neuromuscular disorders ...
Duchenne and Becker muscular dystrophy severity depends upon the nature and location of the DMD gene...
Duchenne muscular dystrophy is caused by mutations in the DMD gene that disrupt the open reading fra...
Muscular dystrophies have historically been characterised according to clinical criteria, however in...
Background: Becker muscular dystrophy (BMD) is caused by mutations in the dystrophin gene with varia...
Deletions giving rise to Duchenne muscular dystrophy (DMD) and the less severe Becker muscular dystr...
DMD gene exons duplications account for up to 5-10 % of Duchenne (DMD) and up to 5-19% of Becker (BM...