Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in young children and infants. There are no approved vaccines or effective antivirals. Alveolar macrophages are known to play an essential role in establishing and resolving the inflammatory response to infection. We have investigated the capacity for alveolar-like macrophages (ALM) generated from stem cells to protect against RSV infection and pathology. We initially established that ALMs are not productively infected by RSV, and co-incubations of ALMs and RSV led to a dose- and time-dependent reduction in viral titer. During in vivo studies, ALM groups were given an intra-tracheal instillation of ALMs prior to infection. Mice given ALMs prior to in...
Tissue resident memory T (Trm) cells act as sentinels and early responders to infection. Respiratory...
Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract infectio...
Background\ud Poor interferon gamma (IFNγ) production during respiratory syncytial virus (RSV) is as...
Respiratory Syncytial Virus (RSV) is the leading cause of acute lower respiratory infections in youn...
Respiratory syncytial virus (RSV) is a major pathogen that infects lower respiratory tract and cause...
Respiratory syncytial virus (RSV) is a significant cause of lower respiratory tract disease in child...
Background: Human respiratory syncytial virus (RSV) is a frequent cause of asthma exacerbations, yet...
Young-Tae Lee,1,* Eun-Ju Ko,1,2,* Hye Suk Hwang,1,2 Jong Seok Lee,1,3 Ki-Hye Kim,1 Young-Man Kwon,1 ...
International audienceLung-resident (LR) mesenchymal stem and stromal cells (MSCs) are key elements ...
ABSTRACT Respiratory syncytial virus (RSV) is a major cause hospitalization of children with resp...
<div><p>Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral death in i...
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections. Immunity ...
Thirteen previously healthy children with acute onset of severe lower respiratory tract signs and sy...
Respiratory Syncytial Virus (RS virus) is the most common cause of lower respiratory tract disease i...
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral death in infants. ...
Tissue resident memory T (Trm) cells act as sentinels and early responders to infection. Respiratory...
Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract infectio...
Background\ud Poor interferon gamma (IFNγ) production during respiratory syncytial virus (RSV) is as...
Respiratory Syncytial Virus (RSV) is the leading cause of acute lower respiratory infections in youn...
Respiratory syncytial virus (RSV) is a major pathogen that infects lower respiratory tract and cause...
Respiratory syncytial virus (RSV) is a significant cause of lower respiratory tract disease in child...
Background: Human respiratory syncytial virus (RSV) is a frequent cause of asthma exacerbations, yet...
Young-Tae Lee,1,* Eun-Ju Ko,1,2,* Hye Suk Hwang,1,2 Jong Seok Lee,1,3 Ki-Hye Kim,1 Young-Man Kwon,1 ...
International audienceLung-resident (LR) mesenchymal stem and stromal cells (MSCs) are key elements ...
ABSTRACT Respiratory syncytial virus (RSV) is a major cause hospitalization of children with resp...
<div><p>Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral death in i...
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections. Immunity ...
Thirteen previously healthy children with acute onset of severe lower respiratory tract signs and sy...
Respiratory Syncytial Virus (RS virus) is the most common cause of lower respiratory tract disease i...
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral death in infants. ...
Tissue resident memory T (Trm) cells act as sentinels and early responders to infection. Respiratory...
Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract infectio...
Background\ud Poor interferon gamma (IFNγ) production during respiratory syncytial virus (RSV) is as...