The rise of economic populism and movements for greater racial, gender, and class equality over the last few years have foregrounded the massive problems of spatial and social inequality in the United States. Academic research focused on these disparities increasingly suggests that a mix of rising economic inequalities across the U.S. urban system, as well as inadequate attention to deep historical economic injustices, have eroded economic mobility for many people and places. Providing concrete solutions to this issue is a thorny problem for social science and policy which requires that we address inter-regional, intra-regional, and inter-personal inequalities, as well as their interconnections. The following chapters argue that a relationa...